Authors:

  • Barrett, Meredith A.
  • Humblet, Olivier
  • Hiatt, Robert A.
  • Adler, Nancy E.

Abstract:

Big data is often discussed in the context of improving medical care, but it also has a less appreciated but equally important role to play in preventing disease. Big data can facilitate action on the modifiable risk factors that contribute to a large fraction of the chronic disease burden, such as physical activity, diet, tobacco use, and exposure to pollution. It can do so by facilitating the discovery of risk factors for disease at population, subpopulation, and individual levels, and by improving the effectiveness of interventions to help people achieve healthier behaviors in healthier environments. In this article, we describe new sources of big data in population health, explore their applications, and present two case studies illustrating how big data can be leveraged for prevention. We also discuss the many implementation obstacles that must be overcome before this vision can become a reality.

Document:

https://www.liebertpub.com/doi/full/10.1089/big.2013.0027?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

  • References
    • 1 National Research Council and Institute of Medicine. U.S. Health in International PerspectiveShorter Lives, Poorer Health. Panel on Understanding Cross-National Health Differences Among High-Income CountriesWashington, DCThe National Academies Press2013.1. National Research Council and Institute of Medicine. U.S. Health in International Perspective: Shorter Lives, Poorer Health. Panel on Understanding Cross-National Health Differences Among High-Income Countries. Washington, DC: The National Academies Press, 2013. Google Scholar
    • 2 McGinnis JFoege WActual causes of death in the United StatesJAMA199327022072212.2. McGinnis J, Foege W. Actual causes of death in the United States. JAMA 1993; 270:2207–2212. Crossref, MedlineGoogle Scholar
    • 3 Mokdad AMarks JStroup Det al.Actual causes of death in the United States, 2000JAMA200429112381245.3. Mokdad A, Marks J, Stroup D, et al. Actual causes of death in the United States, 2000. JAMA 2004; 291:1238–1245. Crossref, MedlineGoogle Scholar
    • 4 National Center for Health Statistics. Health, United States, 2011With Special Feature on Socioeconomic Status and HealthHyattsville, MDNational Center for Health Statistics2012.4. National Center for Health Statistics. Health, United States, 2011: With Special Feature on Socioeconomic Status and Health. Hyattsville, MD: National Center for Health Statistics, 2012. Google Scholar
    • 5 Wang YCMcPherson KMarsh Tet al.Health and economic burden of the projected obesity trends in the USA and the UKLancet2011378815825.5. Wang YC, McPherson K, Marsh T, et al. Health and economic burden of the projected obesity trends in the USA and the UK. Lancet 2011; 378:815–825. Crossref, MedlineGoogle Scholar
    • 6 Fineberg HVThe paradox of disease prevention: celebrated in principle, resisted in practiceJAMA20133108590.6. Fineberg HV. The paradox of disease prevention: celebrated in principle, resisted in practice. JAMA 2013; 310:85–90. Crossref, MedlineGoogle Scholar
    • 7 Manyika JChui MBrown Bet al.Big Data: The Next Frontier for Innovation, Competition, and ProductivitySan Francisco, CAMcKinsey Global Institute2011.7. Manyika J, Chui M, Brown B, et al. Big Data: The Next Frontier for Innovation, Competition, and Productivity. San Francisco, CA: McKinsey Global Institute, 2011. Google Scholar
    • 8 Chawla NVDavis DABringing big data to personalized healthcare: A patient-centered frameworkJ Gen Intern Med2013June25[Epub ahead of print]8. Chawla NV, Davis DA. Bringing big data to personalized healthcare: A patient-centered framework. J Gen Intern Med 2013, June 25. [Epub ahead of print] Crossref, MedlineGoogle Scholar
    • 9 National Research Council. Toward Precision MedicineBuilding a Knowledge Network for Biomedical Research and a New Taxonomy of DiseaseWashington, DCCommittee on a Framework for Development a New Taxonomy of Disease, National Research Council2011.9. National Research Council. Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease. Washington, DC: Committee on a Framework for Development a New Taxonomy of Disease, National Research Council, 2011. Google Scholar
    • 10 Dyson EThe quantified communityProject SyndicateJuly232012.10. Dyson E. The quantified community. Project Syndicate. July 23, 2012. Google Scholar
    • 11 Nilsen WKumar SShar Aet al.Advancing the science of mHealthJ Health Commun201217510.11. Nilsen W, Kumar S, Shar A, et al. Advancing the science of mHealth. J Health Commun 2012;17:5–10. Crossref, MedlineGoogle Scholar
    • 12 Laney D3D data management: Controlling data volume, velocity, and variety. META Group2001blogs.gartner.com/doug-laney/files/2012/01/ad949-3D-Data-Management-Controlling-Data-Volume-Velocity-and-Variety.pdf12. Laney D. 3D data management: Controlling data volume, velocity, and variety. META Group, 2001. Available online at blogs.gartner.com/doug-laney/files/2012/01/ad949-3D-Data-Management-Controlling-Data-Volume-Velocity-and-Variety.pdf Google Scholar
    • 13 Kumar SNilsen WPavel Met al.Mobile health: Revolutionizing health through transdisciplinary tesearchComputer2012462835.13. Kumar S, Nilsen W, Pavel M, et al. Mobile health: Revolutionizing health through transdisciplinary tesearch. Computer 2012; 46:28–35. CrossrefGoogle Scholar
    • 14 Jutte DPRoos LLBrownell MDAdministrative record linkage as a tool for public health researchAnnu Rev Public Health20113291108.14. Jutte DP, Roos LL, Brownell MD. Administrative record linkage as a tool for public health research. Annu Rev Public Health 2011; 32:91–108. Crossref, MedlineGoogle Scholar
    • 15 Kaplan GAHow big is big enough for epidemiology?Epidemiology2007181820.15. Kaplan GA. How big is big enough for epidemiology? Epidemiology 2007;18:18–20. Crossref, MedlineGoogle Scholar
    • 16 HIMSSA new prescription for chronic disease: Remote monitoring devicesHIMSS Analytics and Qualcomm Life2012.16. HIMSS. A new prescription for chronic disease: Remote monitoring devices. HIMSS Analytics and Qualcomm Life, 2012. Google Scholar
    • 17 Fox SSocial Life of Health InformationWashington, DCPew Research Center2011.17. Fox S. Social Life of Health Information. Washington, DC: Pew Research Center, 2011. Google Scholar
    • 18 Purcell KHalf of adult cell phone owners have apps on their phonesWashington, DCPew Research Center2011.18. Purcell K. Half of adult cell phone owners have apps on their phones. Washington, DC: Pew Research Center, 2011. Google Scholar
    • 19 eHealthAn Issue Brief on eHealth Tools and Diabetes Care for Socially Disadvantaged PopulationsWashington, DCeHealth Initiative2012.19. eHealth. An Issue Brief on eHealth Tools and Diabetes Care for Socially Disadvantaged Populations. Washington, DC: eHealth Initiative, 2012. Google Scholar
    • 20 Smith ASmartphone ownership: 2013 updateWashington, DCPew Research Center2013.20. Smith A. Smartphone ownership: 2013 update. Washington, DC: Pew Research Center, 2013. Google Scholar
    • 21 The World BankInformation and Communications for Development 2012: Maximizing MobileWashington, DCWorld Bank2012.21. The World Bank. Information and Communications for Development 2012: Maximizing Mobile. Washington, DC: World Bank, 2012. CrossrefGoogle Scholar
    • 22 World Economic ForumPersonal Data: The Emergence of a New Asset ClassGeneva, SwitzerlandWorld Economic Forum2011.22. World Economic Forum. Personal Data: The Emergence of a New Asset Class. Geneva, Switzerland: World Economic Forum, 2011. Google Scholar
    • 23 Centers for Medicare and Medicaid ServicesMeaningful Use. Centers for Medicare and Medicaid Services2013.23. Centers for Medicare and Medicaid Services. Meaningful Use. Centers for Medicare and Medicaid Services, 2013. Google Scholar
    • 24 Swan MCrowdsourced health research studies: an important emerging complement to clinical trials in the public health research ecosystemJ Med Internet Res201214e46.24. Swan M. Crowdsourced health research studies: an important emerging complement to clinical trials in the public health research ecosystem. J Med Internet Res 2012; 14:e46. Crossref, MedlineGoogle Scholar
    • 25 Waldrop MBig data: WikiomicsNature200845522.25. Waldrop M. Big data: Wikiomics. Nature 2008; 455:22. Crossref, MedlineGoogle Scholar
    • 26 Ginsberg JMohebbi MHPatel RSet al.Detecting influenza epidemics using search engine query dataNature200845710121014.26. Ginsberg J, Mohebbi MH, Patel RS, et al. Detecting influenza epidemics using search engine query data. Nature 2008; 457:1012–1014. CrossrefGoogle Scholar
    • 27 Butler DWhen Google got flu wrongNature2013494155156.27. Butler D. When Google got flu wrong. Nature 2013; 494:155–156. Crossref, MedlineGoogle Scholar
    • 28 Rothman AToward a theory-based analysis of behavioral maintenanceHealth Psychol200019Suppl 16469.28. Rothman A. Toward a theory-based analysis of behavioral maintenance. Health Psychol 2000; 19(Suppl 1):64–69. Crossref, MedlineGoogle Scholar
    • 29 Carter MCBurley VJNykjaer Cet al.Adherence to a smartphone application for weight loss compared to website and paper diary: Pilot randomized controlled trialJ Med Internet Res201315e32.29. Carter MC, Burley VJ, Nykjaer C, et al. Adherence to a smartphone application for weight loss compared to website and paper diary: Pilot randomized controlled trial. J Med Internet Res 2013; 15:e32. Crossref, MedlineGoogle Scholar
    • 30 Dayer LHeldenbrand SAnderson Pet al.Smartphone medication adherence apps: Potential benefits to patients and providersJ Am Pharm Assoc201353172181.30. Dayer L, Heldenbrand S, Anderson P, et al. Smartphone medication adherence apps: Potential benefits to patients and providers. J Am Pharm Assoc 2013; 53:172–181. Crossref, MedlineGoogle Scholar
    • 31 Robert Wood Johnson FoundationTracking and Sharing observations from daily life could transform chronic care managementProject HealthDesign Blog2010http://www.rwjf.org/en/about-rwjf/newsroom/newsroom-content/2010/03/tracking-and-sharing-observations-from-daily-life-could-transfor.html31. Robert Wood Johnson Foundation. Tracking and Sharing observations from daily life could transform chronic care management. Project HealthDesign Blog, 2010. Available online at http://www.rwjf.org/en/about-rwjf/newsroom/newsroom-content/2010/03/tracking-and-sharing-observations-from-daily-life-could-transfor.html Google Scholar
    • 32 Christakis NAFowler JHThe spread of obesity in a large social network over 32 yearsN Engl J Med2007357370379.32. Christakis NA, Fowler JH. The spread of obesity in a large social network over 32 years. N Engl J Med 2007; 357:370–379. Crossref, MedlineGoogle Scholar
    • 33 Cerin ELee KYBarnett Aet al.Objectively-measured neighborhood environments and leisure-time physical activity in Chinese urban eldersPrev Med2012568689.33. Cerin E, Lee KY, Barnett A, et al. Objectively-measured neighborhood environments and leisure-time physical activity in Chinese urban elders. Prev Med 2012; 56:86–89. Crossref, MedlineGoogle Scholar
    • 34 Robinson PLDominguez FTeklehaimanot Set al.Does distance decay modelling of supermarket accessibility predict fruit and vegetable intake by individuals in a large metropolitan area?J Health Care Poor Underserved201324172185.34. Robinson PL, Dominguez F, Teklehaimanot S, et al. Does distance decay modelling of supermarket accessibility predict fruit and vegetable intake by individuals in a large metropolitan area? J Health Care Poor Underserved 2013; 24:172–185. Crossref, MedlineGoogle Scholar
    • 35 Boulos MNKResch BCrowley DNet al.Crowdsourcing, citizen sensing and sensor web technologies for public and environmental health surveillance and crisis management: trends, OGC standards and application examplesInt J Health Geogr20111067.35. Boulos MNK, Resch B, Crowley DN, et al. Crowdsourcing, citizen sensing and sensor web technologies for public and environmental health surveillance and crisis management: trends, OGC standards and application examples. Int J Health Geogr 2011; 10:67. Crossref, MedlineGoogle Scholar
    • 36 de Nazelle ASeto EDonaire-Gonzalez Det al.Improving estimates of air pollution exposure through ubiquitous sensing technologiesEnviron Poll20131769299.36. de Nazelle A, Seto E, Donaire-Gonzalez D, et al. Improving estimates of air pollution exposure through ubiquitous sensing technologies. Environ Poll 2013; 176:92–99. Crossref, MedlineGoogle Scholar
    • 37 Silvertown JA new dawn for citizen scienceTrends Ecol Evol200924467471.37. Silvertown J. A new dawn for citizen science. Trends Ecol Evol 2009; 24:467–471. Crossref, MedlineGoogle Scholar
    • 38 Kerr JDuncan SSchipperjin JUsing global positioning systems in health research: A practical approach to data collection and processingAm J Prev Med201141532540.38. Kerr J, Duncan S, Schipperjin J. Using global positioning systems in health research: A practical approach to data collection and processing. Am J Prev Med 2011; 41:532–540. Crossref, MedlineGoogle Scholar
    • 39 Elliott PSavitz DADesign issues in small-area studies of environment and healthEnviron Health Perspect20081161098.39. Elliott P, Savitz DA. Design issues in small-area studies of environment and health. Environ Health Perspect 2008; 116:1098. Crossref, MedlineGoogle Scholar
    • 40 Institute of MedicineAccelerating Progress in Obesity Prevention: Solving the Weight of the NationWashington, DCInstitute of Medicine2012.40. Institute of Medicine. Accelerating Progress in Obesity Prevention: Solving the Weight of the Nation. Washington, DC: Institute of Medicine, 2012. Google Scholar
    • 41 Helmerhorst HJBrage SWarren Jet al.A systematic review of reliability and objective criterion-related validity of physical activity questionnairesInt J Behav Nutr Phys Act20129155.41. Helmerhorst HJ, Brage S, Warren J, et al. A systematic review of reliability and objective criterion-related validity of physical activity questionnaires. Int J Behav Nutr Phys Act 2012; 9:1–55. Crossref, MedlineGoogle Scholar
    • 42 Donaire-Gonzalez Dde Nazelle ASeto Eet al.Comparison of physical activity measures using mobile phone-based CalFit and actigraphJ Med Internet Res201315e111.42. Donaire-Gonzalez D, de Nazelle A, Seto E, et al. Comparison of physical activity measures using mobile phone-based CalFit and actigraph. J Med Internet Res 2013; 15:e111. Crossref, MedlineGoogle Scholar
    • 43 Akinbami OJMoorman JEBailey Cet al.Trends in Asthma Prevalence, Health Care Use, and Mortality in the United States, 2001–2010Washington, DCU.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics2012.43. Akinbami OJ, Moorman JE, Bailey C, et al. Trends in Asthma Prevalence, Health Care Use, and Mortality in the United States, 2001–2010. Washington, DC: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 2012. Google Scholar
    • 44 Barnett SBLNurmagambetov TACosts of asthma in the United States: 2002–2007J Allergy Clin Immunol2011127145152.44. Barnett SBL, Nurmagambetov TA. Costs of asthma in the United States: 2002–2007. J Allergy Clin Immunol 2011; 127:145–152. Crossref, MedlineGoogle Scholar
    • 45 Van Sickle DMaenner MBarrett Met al.Monitoring and improving compliance and asthma control: mapping inhaler use for feedback to patients, physicians and payersResp Drug Delivery Europe20131119130.45. Van Sickle D, Maenner M, Barrett M, et al. Monitoring and improving compliance and asthma control: mapping inhaler use for feedback to patients, physicians and payers. Resp Drug Delivery Europe 2013; 1:119–130. Google Scholar
    • 46 Van Sickle DMagzamen STruelove Set al.Remote monitoring of inhaled bronchodilator use and weekly feedback about asthma management: An open-group, short-term pilot study of the impact on asthma controlPloS One20138e55335.46. Van Sickle D, Magzamen S, Truelove S, et al. Remote monitoring of inhaled bronchodilator use and weekly feedback about asthma management: An open-group, short-term pilot study of the impact on asthma control. PloS One 2013; 8:e55335. Crossref, MedlineGoogle Scholar
    • 47 MacDonald CNew technology helps doctors link a patient’s location to illness and treatmentThe Washington PostFebruary42013.47. MacDonald C. New technology helps doctors link a patient’s location to illness and treatment. The Washington Post, February 4, 2013. Google Scholar
    • 48 Weiss KBWagener DKGeographic variations in U.S. asthma mortality: Small-area analyses of excess mortality, 1981–1985Am J Epidemiol1990132107115.48. Weiss KB, Wagener DK. Geographic variations in U.S. asthma mortality: Small-area analyses of excess mortality, 1981–1985. Am J Epidemiol 1990; 132:107–115. Crossref, MedlineGoogle Scholar
    • 49 MacDonald CUsing big data to improve health: Geo-medicine combines pollution and health data to better inform patients, doctors and researchersThe Environmental MagazineNovember12012.49. MacDonald C. Using big data to improve health: Geo-medicine combines pollution and health data to better inform patients, doctors and researchers. The Environmental Magazine, November 1, 2012. Google Scholar
    • 50 Dumbill ELiddy EDStanton Jet al.Educating the next generation of data scientistsBig Data201312127.50. Dumbill E, Liddy ED, Stanton J, et al. Educating the next generation of data scientists. Big Data 2013; 1:21–27. LinkGoogle Scholar
    • 51 Davenport THPatil DData scientist: The sexiest job of the 21st centuryHarv Bus Rev2012907077.51. Davenport TH, Patil D. Data scientist: The sexiest job of the 21st century. Harv Bus Rev 2012; 90:70–77. MedlineGoogle Scholar
    • 52 Adler NBush NRPantell MSRigor, vigor, and the study of health disparitiesProc Natl Acad Sci2012109Suppl 21715417159.52. Adler N, Bush NR, Pantell MS. Rigor, vigor, and the study of health disparities. Proc Natl Acad Sci 2012; 109(Suppl 2):17154–17159. Crossref, MedlineGoogle Scholar
    • 53 DeVore SChampion RWDriving population health through accountable care organizationsHealth Aff2011304150.53. DeVore S, Champion RW. Driving population health through accountable care organizations. Health Aff 2011; 30:41–50. CrossrefGoogle Scholar